In recent years, CPS has become an important research direction of academia, industry, and government agencies as CPS are considered to be following the third wave of world information technology after the computer and the Internet. This workshop aims to bring together several researchers from academia, industry, and government agencies to focus on understanding security challenges and attack surface of modern cyber-physical systems, and architect innovative solutions with the help of cutting-edge technologies like security, trust, privacy for software-defined CPS. The workshop will serve as a forum for sharing experiences and outcomes with protocol design, real testbeds, experimental evaluation, prototyping and empirical characterization of Blockchain and SDN technologies in CPS. It will facilitate discussions on unresolved issues in the field, such as blockchain-based security solutions of critical infrastructures, secure and resilient system architectures, protocols and applications for software CPS environment, and SDN capabilities in critical infrastructures, as well as key challenges facing the software-defined CPS of the future. This workshop will focus on techniques, experiences and lessons learned concerning the state of art for the security, trust, and privacy aspects of CPS along with some open issues.